临床资料:患者,男,25岁,农民,因自幼右眼视力差伴上斜视入院。患者生后发现右眼小,且向内上方偏斜,随年龄增长上斜逐渐加重,拟手术矫正斜视收入院。父母为非近亲结婚,孕期无特殊,否认产伤及手术史,足月顺产,家族中无遗传病史。体格检查示全身未见异常,无智力障碍。眼科检查:视力,右眼指数/15cm, Clinical data: patients, male, 25 years old, farmer, because of his childhood poor eyesight with strabismus admission. Patients found that the right eye after birth is small, and the upper skewed inward, with the increasing age on the ramp gradually increased, to be corrected surgery strabismus admission hospital. Parents as non-relatives married, no special pregnancy, birth defects and surgical history was denied, full-term spontaneous abortion, family history of no genetic disease. Physical examination showed no abnormalities in the whole body, no mental retardation. Eye examination: visual acuity, right eye index / 15cm,