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肿瘤是正常细胞恶变后相继繁殖和生长的产物。细胞恶变的关键在于细胞内遗传物质DNA上的基因发生了突变;这种改变也可以反映在染色质和染色体结构水平上。因此从染色体量或质的变化方面进行探索,也是研究肿瘤的发生、发展,以及肿瘤和遗传关系的一个重要途径。 1976年6月,我省永吉县某镇谭××夫妇生有8女,几年来先后有3女发生了卵巢肿瘤,经医学科学院肿瘤研究所介绍,要求我们为其全家检查染色体,希证实高发卵巢肿瘤是
Tumors are the product of successive propagation and growth of normal cells following malignant transformation. The key to cell malignant transformation is the mutation of the gene in the DNA of the intracellular genetic material; this change can also be reflected in the chromatin and chromosome structure. Therefore, to explore the changes of chromosome mass or mass is also an important way to study the occurrence and development of tumors and the relationship between tumors and heredity. In June 1976, there were 8 women born to Tan × × couple in a town in Yongji county of our province. In the past few years, 3 women and one woman have ovarian tumors. The Institute of Oncology, Chinese Academy of Medical Sciences introduced us and asked us to check the chromosomes for their whole family. Ovarian tumors are