论文部分内容阅读
目的：评价尿激酶静脉溶栓治疗急性ST 段抬高心肌梗死的临床疗效。方法：回顾性分析我院108例尿激酶静脉溶栓治疗的急性ST 段抬高型心肌梗死患者的临床资料，根据尿激酶溶栓启动时间分为发病3h内溶栓组（36例）、3－6h内溶栓组（38例）和6－12h内溶栓组（34例），通过分析、比较血管再通率来评价尿激酶的溶栓疗效。结果108例急性ST 段抬高型心肌梗死患者接受溶栓治疗，血管总再通率为57．41％（62/108），其中发病3h内溶栓组的血管再通率为86．11％（31/36）；3－6h 内溶栓组血管再通率为57．80％（22/38）；6－12h内溶栓组血管再通率为26．47（9/34），三组血管再通率的总体比较及两两比较差异有统计学意义（P＜0．005或 P＜0．01）。结论尿激酶静脉溶栓治疗急性ST 段抬高型心肌梗死疗效可靠，尽早进行尿激酶静脉溶栓治疗可大幅提高血管再通率。“,” Objective :To valuate the clinical effect of thrombolytic therapy with U rokinaes in patients with acute ST -segment elevation myocardial infarction(STENI) .M ethods :The clinical data of one hundred and eight patients with acute ST -segment elevation myocardial infarction underwent thrombolysis therapy by intravenous administering of urokinase were enrolled by retrospective analysis .They were as-signed to three groups according to he time of morbidity :inner 3 hours group(36cases) ,3 to 6 hours group(38cases) and 6 to 12 hours group (34cases) .The recanalizationrate rate after thrombolysis therapy were analyzed and compared among three groups .Results :The total reca-nalizationrate rate of the 108 cases w ho received the treatment of urokinase thrombolysis is 57 .41% .The recanalizationrate rate of inner 3 hours group is 86 .11% (31/36) .The recanalizationrate rates of 3 to 6 hours group and 6 to 12 hours group are 57 .80% (22/38) and 26 .47%(9/34) respectively .The recanalizationrate rates of three groups are significantly different overall (P<0 .005) ,Compared interclass they are also significantly different (P<0 .005 or P<0 .01) .Conclusion :Urokinase thrombolytic therapy of acute ST -segment elevation myocardial infarction has signal clinical effect .Urokinase thrombolytic therapy can greatly improve the recanalization rate as soon as possible .