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虽然骨矿物质的分析有助于检查和治疗骨质疏松症及其它骨代谢疾病,但这一技术却处于艰难时期。为了进行适宜而有效的治疗,需要有能快速准确地检查骨密度逐渐变化的测定方法。一种定量的数字式放射照像的新技术,或称之为X射线吸收测定法已证实具有高的检测精度,可使骨矿物质的分析技术出现新的发展。内科医生对骨密度测定的概念,特别是用于骨质疏松症检查提出了异议。据说令人不满的主要原因是,现有的方法都不能说是最好的。在这些方法中用得最广泛的有单光子吸收测定法(SPA)、双光子吸收测定法(DPA)和定量计算断层扫描摄影法(QCT)。 SPA用于测量远端桡骨及跟骨的骨矿物质含量。虽然它具有费用低、精度高的优点,但人们认为在这些解剖部位所进行的测定与在骨质减少时对发生骨折更为重要的脊柱及髋部的测定关系不大。
Although bone mineral analysis helps to examine and treat osteoporosis and other diseases of bone metabolism, this technique is in a difficult situation. In order to conduct appropriate and effective treatment, there is a need for a rapid and accurate examination of bone mineral density changes in the measurement method. A new quantitative technique for digital radiography, or X-ray absorptiometry, has proved to be highly accurate and can lead to new advances in bone mineral analysis. Physicians have raised objections to the concept of bone mineral density testing, especially for osteoporosis. The main reason which is said to be unsatisfactory is that the existing methods can not be said to be the best. Among these methods are the most widely used single photon absorption (SPA), two-photon absorption (DPA) and quantitative computed tomography (QCT). SPA is used to measure the bone mineral content of the distal radius and calcaneus. Although it has the advantages of low cost and high precision, it is believed that the measurements performed at these anatomical sites are of little relevance to the determination of the spine and hip, which is more important in fractures at the time of osteopenia.