POEMS综合征是一组以多发性感觉运动性周围神经病为突出表现 ,常伴有多系统损害及浆细胞瘤等相关的临床证候群[1 ,2 ] ,临床十分少见。国外对本综合征陆续有所报道 ,国内自 1 985年中国人民解放军第 30 9医院刘培霞首次报道2例 ,迄今为止总共报道 60余例 ,且认识有限。作者收集 POEMS syndrome is a group of clinical syndromes associated with multiple sensory and motor peripheral neuropathy, often accompanied by multiple system damage and plasmacytoma [1, 2], clinically rare. Foreign reports of this syndrome have been reported in succession. Since the first case reported by Liu Peixia of the 30th Hospital of People’s Liberation Army in China from 1985 to 1985, a total of more than 60 cases have been reported so far, with limited understanding. Author collection