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本实验观察了川芎嗪对家兔心肌缺血再灌注损伤时心脏血流动力学异常的影响。结果显示川芎嗪保护组和非保护组比较，左室内压峰值（ＬＶＳＰ）差异显著（Ｐ＜０．０５），左室内压上升最大速率（ＬＶ＋ｄｐ／ｄｔｍａｘ）和左室内压下降最大速率（ＬＶ一ｄｐ／ｄｔｍａｘ）差异均非常显著（Ｐ＜０．０１），表明川芎嗪有保护作用，同时探讨了其可能机理。
This experiment was conducted to observe the effects of tetramethylpyrazine on cardiac hemodynamics during myocardial ischemia/reperfusion injury in rabbits. The results showed that compared with the unprotected group, the left ventricular pressure peak (LVSP) was significantly different (P<0.05), the maximum rate of left ventricular pressure (LV+dp/dtmax) and the maximum rate of left ventricular pressure drop (LV- The difference of dp/dtmax was significant (P<0.01), indicating that Ligustrazine had a protective effect and its possible mechanism was discussed.