论文部分内容阅读
通常,血清中抗体浓度都用滴度来表示,每一份血清都以仍能对试验起反应的最高稀释度作为它的滴度。然而,所谓“最高稀释度”实际上并非确为最高,所以在用传统的公式计算几何均数时就存在一些问题。问题的本质是由于用传统公式计算几何均数时实际上取了每个组区间的下限而不取组中值造成的。本文提出一种改进的计算方法和公式,并介绍了利用滴度数据作 t检验和 F 检验的简化法,并以数字实例说明了其计算方法。
In general, serum antibody concentrations are expressed in terms of titer, and each serum has its titer as the highest dilution that can still react to the test. However, the so-called “maximum dilution” is not actually the highest, so there are some problems when using the traditional formula to calculate the geometric mean. The essence of the problem is due to the fact that when the geometric mean is calculated using the traditional formula, the lower limit of each group interval is actually taken instead of the median value of the group. This paper proposes an improved calculation method and formula, and introduces a simplified method using titer data for t-test and F-test, and illustrates its calculation method with numerical examples.