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目的:观察米索前列醇联合缩宫素预防剖宫产术中宫缩乏力性出血的疗效。方法:选择2012年1月~2013年10月期间在定西市安定区妇幼保健站住院行子宫下段剖宫产200例,随机分为实验组100例(米索前列醇配合缩宫素组)和对照组100例(缩宫素组)。前者在术中胎儿娩出后即将米索前列醇0.2 mg舌下含服,同时缩宫素20 U宫壁注射,后者常规宫壁注射缩宫素20 U,比较两组产后出血情况。结果:两组产妇均无妊娠合并症,无年龄及胎方位限制,米索前列醇配合缩宫素组产后出血发生率明显低于缩宫素组(P<0.01),产后2 h,24 h平均出血量也明显减少(P<0.01)。结论:米索前列醇配合缩宫素预防宫缩乏力性出血效果良好,且使用方便、安全。
Objective: To observe the efficacy of misoprostol combined with oxytocin in the prevention of uterine bleeding in cesarean section. Methods: From January 2012 to October 2013, 200 cases of cesarean section in the lower uterine segment of hospitalized women and children in Anding District, Dingxi City were randomly divided into experimental group (misoprostol with oxytocin group) and Control group of 100 patients (oxytocin group). The former intraoperative fetus immediately after the delivery of misoprostol 0.2 mg sublingual sublingual 20 oxytocin injection of the uterine wall, the latter the conventional uterine wall injection of oxytocin 20 U, postpartum hemorrhage compared two groups. Results: The incidence of postpartum hemorrhage in misoprostol group was significantly lower than that in oxytocin group (P <0.01). The incidence of postpartum hemorrhage in both groups was no significant difference in gestational age, The average amount of bleeding was also significantly reduced (P <0.01). Conclusion: Misoprostol combined with oxytocin to prevent uterine bleeding is effective and easy to use and safe.