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近几年,从分子水平对 HBV 的生物学、病毒和宿主细胞相互作用的研究已取得重要进展。应用 DNA 重组技术,已把 HBV 基因克隆化。它的详细结构,业已确定。现将有关情况分述于下一、HBV 结构HBV 颗粒直径约有42nm,包括一个28nm 具有电子密度的核心结构(核衣壳)和7nm 的包膜。包膜含有 HBsAg。不完整病毒颗粒(22nm 圆形和管状结构)也具有HBsAg 决定簇。核衣壳含有 HBcAg 和其隐匿的抗原决定簇——e 抗原、DNA 以及联接
In recent years, important progress has been made in the research on the interaction between HBV biology and viruses and host cells at the molecular level. Using DNA recombination technology, the HBV gene has been cloned. Its detailed structure, has been identified. Now the situation is divided into the next, the HBV structure of HBV particles about 42nm in diameter, including a 28nm electron density of the core structure (nucleocapsid) and 7nm envelope. Envelope contains HBsAg. Incomplete virus particles (22 nm round and tubular structures) also have HBsAg determinants. The nucleocapsid contains HBcAg and its occult epitopes - e antigen, DNA, and ligation