川楝素是川楝子、苦楝皮的主要成分,目前被广泛应用于农业、医药、生理等研究领域。本文通过检索Pubmed及CNKI数据库中相关文献,主要介绍川楝素及川楝子、苦楝皮提取物的主要研究成果,包括其毒性、驱虫、抗肉毒,尤其是抗肿瘤的药理作用及其机制,以期为基于该化合物的研究和发展提供基础。 Toosendanin is the main component of Toosendan Chinensis and Melia azedarach, which is widely used in the field of agriculture, medicine, physiology and other fields. In this paper, we searched the Pubmed and CNKI database to introduce the main research results of toosendanin, toosendanin and neem bark extract, including its toxicity, deworming, anti-botulism, especially anti-tumor pharmacological effects and its mechanism , In order to provide a basis for the research and development of the compound.