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使用透射电镜观察了10例肝硬化门脉高压症患者胃体部粘膜内毛细血管的超微结构改变,并对无慢性肝病的7例胃体部胃炎及5例内镜所见正常者进行了比较性研究。发现肝硬化门脉高压症胃粘膜内毛细血管显著扩张,内皮细胞的胞浆显著变薄;毛细血管的窗孔明显增多、增宽;有些内皮细胞上见有缺陷;而胃粘膜炎性细胞浸润相对较轻。作者认为门脉高压症中胃粘膜损害称为‘充血性胃病’似更为合适。
Transmission electron microscopy was used to observe the ultrastructural changes of the mucosal capillaries in 10 patients with cirrhosis and portal hypertension and 7 patients with gastritis and 5 patients with normal endoscopy without chronic liver disease Comparative research. Found in cirrhotic patients with portal hypertension gastric mucosal significant dilatation of capillaries, endothelial cells significantly thinning of the cytoplasm; capillary window was significantly increased, widened; some endothelial cells see defects; and gastric mucosal inflammatory cell infiltration Relatively light. The authors believe that gastric mucosal damage in portal hypertension called ’congestive stomach’ seems more appropriate.