Purpose: To evaluate the possibility as well as the usage of adaptive optics in high-resolution retinal imaging.Methods: From March to November 2001, the fundus of 25 adults were checked by using Optic Adaptive Retinal Imaging System (OAS) . The age of the subjects varied from 18-48 years. All had normal visual acuity from 0. 9 to 1.0. No abnormality was found in the ocular examination, and their medical as well as ocular history was unremarkable. Results : High-resolution images of the retinal cells, photoreceptor and bipolar cell, were analysed. In these images, the cells are clearly resolved. The density of the photoreceptor at area 1. 5 degree from the foveloa is around 40000 -50000/mm2. At area 3 degree, it drops to less than 30000/mm2.Conclusion:Optic Adaptive Retinal Imaging System (AOS) is able to get high-resolution image of retinal cells in living human eyes. It may be widely used in ophthalmology experimentally and clinically. Eye Science 2002; 18: 131 - 135. Purpose: To evaluate the possibility as well as the usage of adaptive optics in high-resolution retinal imaging. Methods: From March to November 2001, the fundus of 25 adults were checked by using Optic Adaptive Retinal Imaging System (OAS). The age of the subjects varied from 18-48 years. All had normal visual acuity from 0. 9 to 1.0. No abnormality was found in the ocular examination, and their medical as well as ocular history was unremarkable. Results: High-resolution images of the retinal The density of the photoreceptor at area 1. 5 degree from the foveloa is around 40000 -50000 / mm2. At area 3 degree, it drops to less than 30000 / mm2.Conclusion: Optic Adaptive Retinal Imaging System (AOS) is able to get high-resolution image of retinal cells in living human eyes. It is widely used in ophthalmology experimentally and clinically. Eye Science 2002; 18: 131 - 135.