脑内神经回路一旦受损伤,其恢复是相当困难的。但是,神经回路具有相当的可塑性,将胎生期或新生期幼稚神经组织移植人脑内,可使已缺失的脑功能在一定程度上得以恢复。最近几年,瑞典、墨西哥、中国和美国等,为治疗帕金森氏病进行了自体肾上腺髓质脑内移植,瑞典和墨西哥对此作了较为详细的报道。移植后症状改善以墨西哥组较为显著。瑞典组移植方法是将移植片植入尾状核或壳核实质内;而墨西哥组是将贴近尾状核头部的侧脑室表面打孔,使移相片一侧与脑脊液接触,另一侧植入尾状核实质内。从动物实验看,脑室内移植片生存率高,故认为墨西哥组移植方法较好。可是,灵长类在防御机能方面,壳核较尾状核更 Once the brain circuit in the brain is damaged, its recovery is quite difficult. However, the neural circuit has considerable plasticity. Transplantation of embryonic or neonatal naive nerve tissue into the human brain can restore the missing brain function to some extent. In recent years, Sweden, Mexico, China and the United States have conducted autologous adrenal medullary brain transplantation for the treatment of Parkinson’s disease. Sweden and Mexico have reported this in more detail. Post-transplant symptom improvement was more pronounced in the Mexican group. In the Swedish group, transplants were implanted into caudate nucleus or putamen. In Mexico group, the surface of the lateral ventricle close to the caudate nucleus was perforated to make one side of CSF contact with cerebrospinal fluid. On the other side, Into the caudate nucleus within. From animal experiments, intraventricular graft survival rate is high, so that the Mexican group transplantation method is better. However, primates have a more defensive function than putamen