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目的分析梅毒合并艾滋病病毒(HIV)感染者的临床特征,了解其治疗效果。方法对武义县疾病预防控制中心诊治的43例梅毒合并HIV感染病例的资料做回顾性分析。结果 43例病例中,显性梅毒占65.12%、隐性梅毒占34.88%。显性一期梅毒硬下疳大多不典型,可出现多个形态不一的溃疡面。二期梅毒疹皮损较非HIV感染者严重、复杂。经抗梅毒治疗后梅毒甲苯胺红不加热血清学试验(TRUST)阳性的转阴率低,持续时间长,血清固定比例增加。结论梅毒合并HIV感染会加重病情,增加治疗难度。临床工作中必须对所有梅毒患者或HIV感染者同时作梅毒血清学检查和HIV抗体筛查,避免误诊、漏诊。
Objective To analyze the clinical characteristics of syphilis with HIV infection and to understand its therapeutic effect. Methods The data of 43 cases of syphilis with HIV infection diagnosed and treated in Wuyi CDC were analyzed retrospectively. Results In 43 cases, dominant syphilis accounted for 65.12% and latent syphilis accounted for 34.88%. Mostly dominant syphilis dioecium is not typical, there may be a number of different forms of ulcers. Secondary syphilis skin lesions than non-HIV infection were serious and complicated. After treatment with anti-syphilis syphilis toluidine red unheated serological test (TRUST) -positive low negative conversion rate, long duration, increased serum fixation. Conclusion Syphilis with HIV infection will aggravate the condition and increase the difficulty of treatment. Clinical work must be syphilis patients or HIV-infected persons at the same time for syphilis serology and HIV antibody screening to avoid misdiagnosis, missed diagnosis.