一种药物必须能以适当浓度出现在作用部位,通过与受体的相互作用,然后方能引起一定的药理反应。优良的药物除了理化特性适宜与受体相互结合之外,同时也必由于它符合体内转运规律,容易从给药部位到达作用部位,形成有效浓度。各类药物在吸收、分布、排泄等转运过程中,往往表现出各自的特征。决定这些特征的因素很多,譬如组织亲和力的差别,便是原因之一,脂溶性药物如硫喷妥、双苄胺等容易 A drug must be present at the site of action at the appropriate concentration and, through interaction with the receptor, can cause some pharmacological response. In addition to good physical and chemical properties of excellent drugs combined with the receptor, but also because it is consistent with the law of transit in vivo, easy to reach the site of action from the administration site to form an effective concentration. Various types of drugs in the absorption, distribution, excretion and other transport process, often show their own characteristics. There are many factors that determine these characteristics, such as differences in tissue affinity, which is one of the reasons why fat-soluble drugs such as thiopental, bisbenzylamine and the like are easy