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目的:了解涉县出生缺陷的发生率及顺位,分析其与三级预防的关系,提出相应干预措施,以降低涉县出生缺陷的发生率。方法:对涉县2005～2009年4所县级以上监测点医院的出生缺陷监测资料进行分析。结果:5年间涉县出生缺陷发生率呈波动式变化,总体呈上升趋势,5年出生缺陷平均发生率为11.14‰(247/22 178),出生缺陷前5位依次为:脊柱裂、总唇腭裂、多指、肛门闭锁、肢体短缩。而脊柱裂和总唇腭裂5年间始终居前二位。围产儿缺陷发生率以<20岁孕妇组最高,其次为>35岁孕妇组,25～30岁孕妇组发生率最低。结论:2005年～2009年出生缺陷发生率呈上升趋势,重点加强出生缺陷三级预防工作,做好孕前、孕期保健、产前筛查及产前诊断工作,降低缺陷儿的出生率,提高出生人口素质。
Objective: To understand the incidence and rank of birth defects in Shexian County, analyze its relationship with tertiary prevention and put forward corresponding intervention measures to reduce the incidence of birth defects in Shexian County. Methods: The surveillance data of birth defects in 4 hospitals above the county level from 2005 to 2009 in Shexian county were analyzed. Results: The incidence of birth defects in Shexian County fluctuated in five years with an overall upward trend. The average incidence of five-year birth defects was 11.14 ‰ (247/22 178). The top five birth defects were as follows: spina bifida, total lip Cleft palate, multiple fingers, anal atresia, limb shortening. The spina bifida and total cleft lip and palate 5 years always top two. The incidence of perinatal defects in <20-year-old pregnant women group was highest, followed by> 35-year-old pregnant women group, 25-30-year-old pregnant women group the lowest incidence. Conclusion: The incidence of birth defects is on an upward trend from 2005 to 2009, with a focus on tertiary prevention of birth defects, pre-pregnancy and prenatal care, prenatal screening and prenatal diagnosis, reducing birth defects and increasing births Quality.