论文部分内容阅读
抢救失血性休克关键是判定出血灶,积极止血井快速输液补足循环血量。目前在美国主张先输晶体液,只在血细胞比容(Hct)达30%时才启用输血(transfusion trigger)。限用血液的理由之一是害怕传播爱滋病毒。为了研究严重失血性休克单用晶体液的效果,作者将 Sprague-Dawley 雄鼠(n=85)制成创伤失血体克模型,先正中切开动物腹壁造成创伤,缝合恢复后,在10分钟内放血使平均动脉压(MAP)降到40 mmHg,继续放血到动脉不能代偿称为极量失血(MBV),再按50%MBV 输乳酸盐林
The key to rescue hemorrhagic shock is to determine the hemorrhage, positive rapid hemostatic wells make up for circulating blood volume. At present, the United States advocates the first transfusion of fluid, transfusion trigger only when hematocrit (Hct) up to 30%. One of the reasons for blood restrictions is fear of transmitting HIV. In order to investigate the effect of single crystalloid solution on severe hemorrhagic shock, the authors used a Sprague-Dawley male rat (n = 85) to make a model of traumatic bleed and blood loss. First, Bleeding reduced the mean arterial pressure (MAP) to 40 mmHg, continued bleeding to the artery and compensated for MBF, followed by 50% MBV lactobionate