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本文对６０例海洛因依赖者外周血淋巴细胞微核发生率（简称微核率）进行研究观察。结果表明：吸毒并肝损伤组、吸毒无肝损伤组和非吸毒肝损伤组的微核率均明显高于健康人对照组（Ｐ＜０．０１）。吸毒并肝损伤组的微核率虽高于非吸毒肝损伤组，但均无统计学上差异，结果提示，吸毒人群微核率增高，其原因，除海洛因直接影响外，还可能与海洛因的不纯或使用过程中有肝炎病毒感染有关。
In this paper, 60 cases of heroin addicts in peripheral blood lymphocytes micronucleus incidence (referred to as micronucleus rate) were observed and studied. The results showed that the micronucleus rate of drug-induced liver injury group, drug-induced liver injury group and non-drug-induced liver injury group were significantly higher than those of healthy control group (P <0.01). Although the micronucleus rate of drug-induced and liver injury group was higher than that of non-drug-induced liver injury group, there was no statistical difference. The results suggested that the micronucleus rate of drug addicts increased, which may be related to the direct effect of heroin, Impure or use during the hepatitis virus infection.