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地中海贫血是不少见的一种贫血。它的病因是胎生期血红蛋白残存。这是由于血红蛋白生长障碍。当然,基因缺陷是它的本质。利用基因工程技术来诊断这种基因缺陷是临床应用基因工程一个突破口。 Stuart H.Orkin等七人合作实现了利用限制性内切酶分解胎儿羊水中纤维母细胞的DNA。
Thalassemia is not uncommon for anemia. Its etiology is the neonatal hemoglobin remnants. This is due to hemoglobin growth disorders. Of course, genetic defects are its essence. The use of genetic engineering techniques to diagnose this genetic defect is a breakthrough in clinical application of genetic engineering. Stuart H.Orkin seven people cooperate to achieve the use of restriction endonucleases in fetal amniotic fluid fibroblast DNA.