目的:比较经鼻间歇正压通气与机械通气在新生儿呼吸窘迫综合征的治疗方面所取得的临床效果。方法:选择曾于我院进行治疗的80例呼吸窘迫综合征新生儿,将其分为两组,每组各有40例,分别作为对照组与观察组,两组均给予肺表面活性物质及常规药物治疗,对照组中患者利用机械通气方法来进行治疗,观察组中患者利用经鼻间歇正压通气方法来进行治疗,在完成治疗之后,对两组患者的治疗效果进行观察,观察比较两组患者的治疗时间,比较两组患者在治疗前后的动脉血气变化情况,比较两组患者在治疗前后的氧合指数以及所出现的并发症。结果:在完成治疗之后,对两组患的治疗时间、动脉血气变化情况、氧合指数以及所出现的并发症进行比较,观察组中的治疗时间、动脉血气变化情况、氧合指数均优秀于对照组,两组患者之间有显著差异存在,观察组中患者治疗有效率达到90.0%,对照组中患者的治疗有效率为70.0%,两组患者之间存在明显差异,观察组中所出现的并发症要少于对照组。结论:对于患有呼吸窘迫征新生儿,利用经鼻间歇正压通气方法进行治疗,能够取得较好的临床效果,治疗有效率较高,并且所出现的并发症也较少,是现代临床上一种治疗新生儿呼吸窘迫综合征的重要方法,有着重要的作用和意义,值得进行推广。 Objective: To compare the clinical effects of nasal intermittent positive pressure ventilation and mechanical ventilation in the treatment of neonatal respiratory distress syndrome. Methods: Eighty neonates with respiratory distress syndrome who had been treated in our hospital were divided into two groups, 40 cases in each group, which served as control group and observation group respectively. Both groups were given pulmonary surfactant and The patients in the control group were treated by mechanical ventilation. The patients in the observation group were treated by nasal intermittent positive pressure ventilation. After completing the treatment, the therapeutic effects of the two groups of patients were observed. Group treatment time, compared two groups of patients before and after treatment of arterial blood gas changes in both groups before and after treatment compared oxygenation index and the complications. Results: After the completion of treatment, the treatment time, arterial blood gas changes, oxygenation index and the complications were compared between the two groups. The treatment time, arterial blood gas changes and oxygenation index in the observation group were all excellent The control group, there was a significant difference between the two groups of patients, the observation group, the effective rate of treatment of patients reached 90.0%, the control group, the effective rate of treatment was 70.0%, there was a significant difference between the two groups of patients appeared in the observation group The complications were less than the control group. Conclusion: For neonates with respiratory distress syndrome, the use of nasal intermittent positive pressure ventilation for treatment, to achieve better clinical results, the treatment of high efficiency, and the complications are less, is a modern clinical An important method of treatment of neonatal respiratory distress syndrome has an important role and significance and is worth promoting.