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目的评价1CU可调节后房型人工晶状体(IOL)眼的视觉质量,并与非球面单焦点IOL眼进行比较。设计非随机对照试验。研究对象老年性白内障患者118例(118眼)。方法白内障超声乳化吸除术时植入1CU可调节IOL(1CU组)和非球面IOL(Tecnis ZA9003组)各为59例59眼。术后3个月时检查裸眼及矫正远、近视力,最佳矫正远视力下的近视力,波前像差,调制传递函数,40、63、100cm处对比敏感度,拟调节力,并比较脱近用镜率。主要指标视力、波前像差、调制传递函数值、对比敏感度、拟调节力、脱近用镜率。结果术后3个月1CU组的裸眼近视力(1.06±0.24)和最佳矫正远视力下的近视力(1.02±0.13)优于TecnisZA9003组(分别为0.43±0.14、0.43±0.11)(t=8.85,P=0.00;t=13.05,P=0.00)。调节幅度1CU组为(2.58±0.37)D,大于非球面IOL组的(1.46±0.25)D(t=14.33,P=0.00)。1CU组3mm、5mm瞳孔下的球差(0.34±0.06、0.36±0.06)和总像差(0.47±0.14、0.490.14)均大于TecnisZA9003组(分别为0.06±0.06、0.07±0.04,0.30±0.07、0.30±0.58)(3mm瞳孔下t=18.48,P=0.00;t=5.70,P0.00。5mm瞳孔下t=19.98,P=0.00;t=6.70,P=0.00)。在40、63cm1CU组视锐度得分(VAS)分值高于TecnisZA9003组(t=3.64P=0.00;t=2.74,P=0.00;t=2.65,P=0.00;t=2.44,P=0.01)。脱近用镜率1CU组(85%)优于TecnisZA9003组(25%)(χ2=41.95,P0.00)。结论虽然1CU可调节后房型IOL对比敏感度较非球面单焦点IOL有损失,但可获得良好远、中、近视力,适合于迫切要求脱镜的患者。
Objective To evaluate the visual quality of anterior chamber intraocular lens (IOL) with 1CU and to compare with aspherical single-focus IOL eye. Design non-randomized controlled trials. A total of 118 patients (118 eyes) with senile cataract were included in this study. Methods Fifty-nine eyes (59 eyes) were treated with 1U adjustable IOL (1CU group) and aspheric IOL (Tecnis ZA9003 group) during cataract phacoemulsification. At 3 months after operation, the visual acuity, wavefront aberration, modulation transfer function, contrast sensitivity at 40, 63 and 100 cm, and the accommodative power were compared between the naked eye and the correction distance, near vision, and best corrected distance vision Close to the mirror. The main indicators of visual acuity, wavefront aberration, modulation transfer function value, contrast sensitivity, to adjust the power, close to the mirror rate. Results Compared with TecnisZA9003 group (0.43 ± 0.14 and 0.43 ± 0.11, respectively), the visual acuity (1.06 ± 0.24) in the OCU group and 1.02 ± 0.13 in the best corrected distance vision group at 3 months after operation were significantly higher than those in the TecnisZA9003 group (t = 8.85, P = 0.00; t = 13.05, P = 0.00). The amplitude of adjustment was (2.58 ± 0.37) D in 1CU group and (1.46 ± 0.25) D in aspheric IOL group (t = 14.33, P = 0.00). The spherical aberrations (0.34 ± 0.06,0.36 ± 0.06) and total aberrations (0.47 ± 0.14, 0.490.14) in the 3-mm and 5-mm pupils of the 1CU group were larger than those of the TecnisZA9003 group (0.06 ± 0.06, 0.07 ± 0.04 and 0.30 ± 0.07, respectively , 0.30 ± 0.58) (3mm pupil t = 18.48, P = 0.00; t = 5.70, P.00.5mm pupil t = 19.98, P = 0.00; t = 6.70, P = 0.00). Visual acuity scores (VAS) scores were higher in the 40,63 cm group than in the TecnisZA 9003 group (t = 3.64 P = 0.00; t = 2.74, P = 0.00; t = 2.65, P = 0.00; . Closure with the mirror rate 1CU group (85%) is superior to TecnisZA9003 group (25%) (χ2 = 41.95, P <0.001). Conclusion Although the contrast sensitivity of posterior chamber IOL with 1U adjustable posterior chamber IOL is less than that of aspherical single focal IOL, it can obtain good far, moderate and near visual acuity and is suitable for patients who are urgently required to take the lens off.