分子印迹技术是近年发展起来的一种新颖的有机合成手段。评述了分子印迹聚合物的制备方法及尚有待深入的关键问题,重点介绍了分子印迹聚合物用作催化剂在有机合成中应用的优势及研究近况,特别是用作手性催化剂不对称合成光学活性物质。并设计将分子印迹聚合物用于催化醛酮不对称还原反应,可获得较高光学产率的手性醇,其％e.e值达95％以上。 Molecular imprinting technology developed in recent years is a novel means of organic synthesis. The preparation methods of molecularly imprinted polymers and the key issues to be further discussed are reviewed. The advantages and recent applications of molecularly imprinted polymers as catalysts in organic synthesis are reviewed. In particular, asymmetric synthesis of optically active materials as chiral catalysts . The molecularly imprinted polymer was designed to catalyze the asymmetric reduction of aldehydes and ketones. The higher optical yield of chiral alcohol was obtained, and its% e.e value was over 95%.