粘液性水肿昏迷的病因虽然尚不清楚,但寒冷、感染、中枢神经系统抑制剂的使用、肺泡通气低下和低钠血症等因素均可为诱因。作者报道1例β-阻滞剂诱发粘液性水肿昏迷的患者。患者女性,65岁。因意识丧失入院。患者在50岁之前健康良好,但此后即患便秘、不能耐寒和思考迟钝。入院前1年其体重增加了10kg,入院前2个月因高血压曾用β-阻滞剂盐酸 Bufetolol,每次15mg,每日3次。入院时患者神志半清,体温35.5℃,血压160/105mmHg,呼吸14/min,皮肤干燥,面部浮肿,神 Although the etiology of myxedema coma is not clear, factors such as cold, infection, use of CNS depressants, poor alveolar hypoventilation, and hyponatremia may be motivating factors. The authors report 1 patient with β-blocker-induced mucoid edema coma. Patient female, 65 years old. Loss of consciousness due to admission. The patient was healthy before the age of 50, but then became constipated, unable to tolerate cold, and was slow to think. One year before admission, the weight increased by 10kg. Two months before admission, β-blocker hydrochloride (Bufetolol) was used 15mg daily for 3 times because of high blood pressure. Patients admitted to hospital consciousness half body temperature 35.5 ℃, blood pressure 160 / 105mmHg, breathing 14 / min, dry skin, facial edema, God