肝细胞生长因子(hepatocyte growthfactor,H GF)是一种多效性细胞因子,是由NAKAM URA等于1984年从部分肝切除大鼠血清中分离得到,因其能刺激原代培养肝细胞生长和合成,将其命名为H GF。自从H GF发现至今,国内外对其做了许多研究,对它的来源、结构、功能乃至基因序列都有了较为 Hepatocyte growth factor (HGF) is a pleiotropic cytokine isolated from the serum of partially hepatectomized rats by NAKAM URA et al. In 1984 as it stimulates primary cultured hepatocytes to grow and synthesize , Named it H GF. Since the discovery of H GF so far, many studies have been done at home and abroad on its origin, structure, function and even gene sequence