梗阻性黄疸是临床较常见的病理状态,常导致严重肝肾功能损伤、凝血机能障碍、免疫功能低下等损害,其中最主要的是肝脏损伤,也是其他并发症的重要诱因。本文就梗阻性黄疸时一氧化氮的发生机制,以及对影响肝细胞功能的胆汁酸、内毒素途径的认识现状作一综述。1梗阻性黄疸时的病理 Obstructive jaundice is a more common clinical pathological state, often leading to severe liver and kidney dysfunction, coagulation disorders, immune dysfunction and other damage, the most important of which is liver damage, but also an important incentive for other complications. This article reviews the mechanism of nitric oxide in obstructive jaundice, as well as the status quo of understanding the pathways of bile acids and endotoxins that affect hepatocyte function. 1 obstructive jaundice when the pathology