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比较基因组杂交(comparative genomic hy-bridization,CGH)是一种在FISH技术的基础上发展起来的分子细胞遗传学方法,经一次染色体原位杂交实验即可在全部染色体或染色体区域水平对不同基因组间DNA序列拷贝数进行检测并定位。
Comparative genomic hy-bridization (CGH) is a molecular cytogenetic method developed on the basis of FISH technology. After a chromosome in situ hybridization experiment can be carried out at the entire chromosome or chromosome region level between different genomes DNA sequence copy number detection and localization.