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目的从病理学角度分析新生儿先天性心脏病围手术期的死亡原因。方法收集15例围手术期死亡的新生儿先天性心脏病尸检病例,复查病理资料,分析其死亡原因。结果先天性心脏病新生儿围手术期病死率为28·6%,尸检率为62·5%。临床与尸检病理诊断符合率为86·67%,主要死因包括心脏原因(9例),肺部感染(4例)及应激性肾上腺出血(2例)。结论加强新生儿先天性心脏病围手术期的心肺保护,加强尸检意识,有助提高手术成功率。
Objective To analyze the causes of perioperative death in neonates with congenital heart disease from the perspective of pathology. Methods Fifteen cases of perinatal congenital heart disease autopsy died during perioperative period were collected. Pathological data were reviewed and their causes of death were analyzed. Results Perioperative mortality was 28.6% in neonates with congenital heart disease and 62.5% in autopsy. The coincidence rate of pathological diagnosis between clinical and autopsy was 86.67%. The main causes of death were cardiac cause (9 cases), pulmonary infection (4 cases) and stress adrenal hemorrhage (2 cases). Conclusion To strengthen perinatal cardiopulmonary protection in neonates with congenital heart disease and to strengthen the consciousness of autopsy can help to improve the success rate of surgery.