大多数学者认为原发性开角青光眼(POAG)的发病同遗传因素有关,有人证实POAG 病人子女及直系亲属发病率高,POAG 病人的杯盘比,对类固醇激素的敏感性及眼内压水平有一定的遗传倾向。并认为POAG 属于一种多基因多因子常染色体显性或隐性遗传,但确切的发病机制目前仍不十分清楚。为了探讨POAG 同遗传的关系。一些学者做了HLA 同POAG 相关性研究,但结果很不一致,甚至互相矛盾,极少 Most scholars believe that the incidence of primary open-angle glaucoma (POAG) with the genetic factors, it has been confirmed POAG patients with children and immediate family members of the high incidence of POAG patients with cup ratio, the sensitivity to steroids and intraocular pressure Have a certain genetic predisposition. And that POAG belongs to a multi-gene multi-factor autosomal dominant or recessive inheritance, but the exact pathogenesis is still not very clear. In order to explore the POAG genetic relationship. Some scholars do HLA and POAG correlation studies, but the results are very inconsistent or even contradictory, very few