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本文介绍了应用丙戊酸钠治疗小儿癲痫100例,男65例,女35例,年龄由8月至12岁,其中4～12岁占72%,平均病程为18.4月,剂量每天20～50mg/kg,疗程由6月至36月。平均疗程为19.75月。疗效:控制59%,显效21%,有效7%,总有效率为87%。本品对各种类型癲痫均有效,其中对大发作和失神发作疗效更好,本组该两类型79例,有效者达94彩(74/79)。丙戊酸钠常见的副作用为胃肠道功能紊乱,如食欲减退、恶心、呕吐等,多为轻微且一过性,但少数病例有明显食欲减退或食欲亢进。本组36例,血小板计数下降,应引起注意。
This article describes the application of sodium valproate treatment of 100 cases of pediatric epilepsy, 65 males and 35 females, aged from August to 12 years, of which 4 to 12 years accounted for 72%, the average duration of 18.4 months, the dose of 20 ~ 50mg / kg, treatment from June to 36 months. The average course of treatment is 19. 75 months. Efficacy: control 59%, effective 21%, effective 7%, the total effective rate was 87%. This product is effective for all types of epilepsy, of which the treatment of seizures and missed seizures better, the two groups of 79 cases, the effective rate of 94 (74/79). Common side effects of sodium valproate gastrointestinal disorders, such as loss of appetite, nausea, vomiting, mostly mild and transient, but a few cases of significant loss of appetite or loss of appetite. The group of 36 cases, decreased platelet count, should be noted.