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目的:观察右美托咪定在气管异物取出术中对患儿呼吸、循环及术后恢复情况的影响。方法:40例行气管异物取出术患,随机分为右美托咪定组(D组)(n=20)和生理盐水组(S组)(n=20),分别在麻醉诱导前10min静脉输注右美托咪定0.8μg/kg和等容量的生理盐水,输注时间为10min。术中高频射流呼吸机给氧,保持患儿自主呼吸,泵注丙泊酚和瑞芬太尼维持麻醉。结果:D组患儿术中屏气、咳嗽、喉痉挛、术中SP02<90%显著低于S组(P<0.05);D组丙泊酚及瑞芬太尼用量减少(P<0.05)。结论:在气管异物取出术中应用右美托咪定有很大的优势,对呼吸系统影响小,血流动力学平稳,术后并发症少。
Objective: To observe the effect of dexmedetomidine on respiration, circulation and postoperative recovery in children with removal of tracheal foreign bodies. Methods: Forty patients with tracheal foreign bodies were randomly divided into two groups: the dexmedetomidine group (group D) (n = 20) and the saline group (group S) (n = 20) Infusion of dexmedetomidine 0.8μg / kg and equal volume of saline, infusion time was 10min. Intraoperative high-frequency jet ventilator oxygen, to maintain spontaneous breathing, pump propofol and remifentanil to maintain anesthesia. Results: In group D, breath-holding, coughing and laryngospasm were detected during operation. The SP02 <90% was significantly lower in group D than in group S (P <0.05). The dosage of propofol and remifentanil in group D was decreased (P <0.05). Conclusion: The application of dexmedetomidine in the removal of tracheal foreign bodies has great advantages, less impact on the respiratory system, stable hemodynamics and less postoperative complications.