肺表面活性剂对降低肺泡表面张力,维持肺泡的稳定性,建立有效呼吸有重要意义。肺泡表面活性物质的灭活,是肺损伤和某些新生儿呼吸衰竭的重要因素。本文作者观察了应用小牛肺表面活性物质提取物治疗足月新生儿呼吸衰竭的疗效。本文观察的14例中,7例为新生儿肺炎,7例为胎粪吸入综合征。均分别经气管内插管给予小牛肺表面活性物质提取物,剂量为90mg/kg,每6小时1次,最大剂量为4 Pulmonary surfactant is important for reducing alveolar surface tension, maintaining the stability of alveoli and establishing effective respiration. Inactivation of alveolar surfactant is an important factor in lung injury and some neonatal respiratory failure. The authors observed the use of calf lung surfactant extract in term neonates with respiratory failure. Of the 14 cases observed in this article, 7 were neonatal pneumonia and 7 were meconium aspiration syndrome. Were given via endotracheal intubation calf pulmonary surfactant extract, a dose of 90mg / kg, every 6 hours 1, the maximum dose of 4