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目的 研究止泻灵对慢性腹泻患儿血细胞自然免疫粘附功能的影响。方法 对 6 0例慢性腹泻患儿随机分为治疗组和对照组。治疗组给予止泻灵 ,对照组给予一般治疗 ,疗程均为 1个月 ,于治疗前和治疗后分别测定患儿红细胞、粒细胞和淋巴细胞自然免疫粘附功能状况。结果 止泻灵治疗组慢性腹泻患儿血细胞自然免疫粘附功能均恢复至正常水平 ,而对照组患儿的血细胞自然免疫粘附功能状况虽然有不同程度的改善 ,但明显低于止泻灵治疗组和正常儿童 ,且治疗组和对照组在治疗后血细胞自然免疫粘附功能状况差异显著 (P <0 .0 1) 。结论 止泻灵可有效改善慢性腹泻患儿血细胞自然免疫粘附功能状况 ,对提高患儿整体免疫功能水平具有重要意义。
Objective To study the effect of Zhixieling on the function of spontaneous immune adhesion of blood cells in children with chronic diarrhea. Methods Sixty children with chronic diarrhea were randomly divided into treatment group and control group. The treatment group was given antidiarrheal and the control group was given general treatment. The course of treatment was 1 month. The immune function of erythrocytes, granulocytes and lymphocytes in children were measured before and after treatment. Results In the Zhixieling treatment group, the spontaneous immune adhesion of blood cells in children with chronic diarrhea returned to normal levels, while in the control group, the natural immune function of blood cells in children with chronic diarrhea was improved to some extent, but was significantly lower than that of Zhixieling Group and normal children. There was significant difference in the immune function of blood cells between treatment group and control group after treatment (P <0.01). Conclusion Zhixieling can effectively improve the function of spontaneous immune adhesion of blood cells in children with chronic diarrhea, which is of great significance to improve the overall immune function in children.