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目的研究非呼吸道感染的金黄色葡萄球菌临床分布和耐药特点,为临床合理有效地控制感染提供依据。方法通过细菌分离鉴定技术和药敏试验方法,对某医院临床送检非呼吸道标本检验结果进行调查与分析。结果从该医院临床送检的非呼吸道标本中共检出金黄色葡萄球菌291株,其中耐甲氧西林金黄色葡萄球菌(MRSA)86株,占29.55%。金黄色葡萄球菌主要分离自分泌物和脓液,但MRSA检出率最高的标本是尿液和穿刺液。MRSA菌株检出最高的科室是重症监护病房(ICU),其次是脑外科和泌尿烧伤科。临床分离的金黄色葡萄球菌对青霉素、红霉素及克林霉素的耐药率较高,MRSA对青霉素全部耐药。结论引起非呼吸道感染的金黄色葡萄球菌,对多种抗菌药物耐药率较高,ICU成为控制金黄色葡萄球菌感染的重点部位。
Objective To study the clinical distribution and drug resistance of Staphylococcus aureus in non-respiratory tract infections and provide the basis for clinical reasonable and effective infection control. Methods Bacterial isolation and identification techniques and drug susceptibility testing methods were used to investigate and analyze the results of non-respiratory specimens from clinical examination in a hospital. Results A total of 291 Staphylococcus aureus isolates were detected in the non-respiratory specimens clinically tested in this hospital, of which 86 were resistant to methicillin-resistant Staphylococcus aureus (MRSA), accounting for 29.55%. Staphylococcus aureus is mainly isolated from secretions and pus, but the highest detection rate of MRSA is urine and puncture fluid. The highest detected strains of MRSA strains were intensive care unit (ICU), followed by brain surgery and urinary burns. Staphylococcus aureus clinical isolates of penicillin, erythromycin and clindamycin higher resistance rate, MRSA resistant to penicillin. Conclusion Staphylococcus aureus, which causes non-respiratory tract infections, has a high rate of resistance to various antimicrobial agents and ICU has become a key site for the control of Staphylococcus aureus infection.