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目的检测并分析无锡地区变应性鼻炎(AR)患者的吸入性变应原。方法采用免疫印迹法体外半定量检测患者血清中7种常见变应原的阳性分布情况。结果 120例常年性AR患者中,85例患者至少对1种以上的变应原呈阳性反应,阳性率70.83%。在检测的7种常见变应原中,78例尘螨(粉尘螨、户尘螨)阳性,比例为65.0%;36例蟑螂阳性,比例为30.0%。尘螨的阳性反应最强,常引起患者中～重度过敏反应。结论尘螨及蟑螂是无锡地区AR患者最主要的吸入性变应原。
Objective To detect and analyze inhalation allergens in patients with allergic rhinitis (AR) in Wuxi area. Methods Western blotting was used to detect the positive distribution of seven common allergens in serum of patients by semiquantitative in vitro. Results Of 120 patients with perennial AR, 85 patients were positive for at least one allergen, with a positive rate of 70.83%. Among the seven common allergens tested, 78 dust mites (dust mites and house dust mites) were positive, accounting for 65.0%; 36 cockroaches were positive, with a proportion of 30.0%. The positive reaction of dust mites strongest, often causing patients with ~ severe allergic reactions. Conclusion Dust mites and cockroaches are the most important inhaled allergens in AR patients in Wuxi.