人眼视网膜的血管发育基本是在足月出生时才发育到位,而早产儿出生时视网膜血管还没有发育完善,这种发育不成熟的血管对血液氧的浓度非常敏感。非生理性的缺氧、吸氧会造成视网膜血管的异常增生。早产儿,特别是低体重儿出生后为了维持生命,常常需要在暖箱内吸氧。过早吸入高浓度氧或长期吸氧,会因视网膜血管异常增生而发生早产儿视网膜病变。早产儿视网膜病变是发生在生命早期、急剧进展的一种增殖性眼底疾病,最终 Human retinal vascular development is basically in full-term birth to develop in place, and premature children born retinal blood vessels have not yet developed, this immature blood vessels of blood oxygen concentration is very sensitive. Non-physiological hypoxia, oxygen can cause abnormal proliferation of retinal blood vessels. Premature babies, especially those with low birth weight, often need to inhale oxygen in the warm box after birth in order to maintain their lives. Premature inhalation of high concentrations of oxygen or long-term oxygen, due to retinal vascular dysplasia and retinopathy of prematurity occurs. Retinopathy in prematurity is a proliferative eye disease that occurs rapidly in the early stages of life and ultimately