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多种生理过程包括细胞的激活、迁移、增殖、分化以及其它的过程需要细胞之间、细胞与细胞外基质之间的直接接触。细胞与细胞和细胞与细胞外基质之间的相互作用是通过几种不同家族的细胞粘附分子所介导的，它们包括整合素、选择素、钙粘着蛋白和免疫球蛋白。细胞粘附分子的商业和治疗潜力在不断提高，新发现的细胞粘附分子以及某些疾病状态下整合素、选择素、免疫球蛋白新作用的发现为诊断性和治疗性药物的研究和开发提供了很好的机会。
A variety of physiological processes, including cell activation, migration, proliferation, differentiation, and other processes, require direct contact between cells and between cells and the extracellular matrix. The interactions between cells and cells and cells and the extracellular matrix are mediated by several different family of cell adhesion molecules, including integrins, selectins, cadherins, and immunoglobulins. The commercial and therapeutic potential of cell adhesion molecules continues to increase. The discovery of newly discovered cell adhesion molecules and the emerging role of integrins, selectins, and immunoglobulins in certain disease states has been the research and development of diagnostic and therapeutic drugs Provided a good opportunity.