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目的观察瑞舒伐他汀治疗血脂异常及消炎的临床疗效。方法 62例血脂异常患者,给予瑞舒伐他汀10mg/n,每晚睡前服用,治疗8周,治疗前后分别测血脂全套及hs-CRP、肝肾功能、酶学全套。结果治疗8周后,总胆固醇下降63.23%、甘油三脂下降42.36%、低密度脂蛋白下降58.63%、载脂蛋白B(ApoB)下降40.38%、高密度胆固醇升高16.86%、载脂蛋白A(ApoA/)ApoB升高76.68%h,s-CRP下降66.8%各项指标治疗前后比较有统计学意义(P<0.05)。结论瑞舒伐他汀调脂治疗及抗动脉炎症安全、有效。
Objective To observe the clinical effect of rosuvastatin on dyslipidemia and anti-inflammatory. Methods Sixty - two patients with dyslipidemia were treated with rosuvastatin 10 mg / n, taken before going to bed every night for 8 weeks. Complete sets of blood lipid and hs - CRP, liver and kidney function were measured before and after treatment. Results After 8 weeks of treatment, total cholesterol decreased 63.23%, triglyceride decreased 42.36%, low density lipoprotein decreased 58.63%, apolipoprotein B (ApoB) decreased 40.38%, high density cholesterol increased 16.86%, apolipoprotein A (ApoA / ApoB increased 76.68% h, s-CRP decreased 66.8% of the indicators before and after treatment was statistically significant (P <0.05. Conclusion rosuvastatin lipid-lowering therapy and anti-arterial inflammation is safe and effective.