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大鼠哮喘连续激发后肺组织胞膜β-AR和脑浆cAMP水平逐日下降，在第7目明显低于正常对照组（P＜0．01）；激发第7日，龟芪散明显上调β-AR密度（P＜0．05）并使cAMP水平明显上升（P＜0．05）。提示龟芪散治疗哮喘可能与其上调β-AR，提高cAMP水平作用有关，联合用药可提高糖皮质激素的疗效。
The levels of β-AR and brain cAMP in the lung tissue of asthmatic rats were gradually decreased after consecutive asthmatic challenge, and were significantly lower in the 7-mesh than in the normal control group (P<0.01). On the 7th day of the challenge, the turtles were significantly up-regulated in β- AR density (P<0.05) increased the cAMP level significantly (P<0.05). It is suggested that the treatment of asthma by Kam Ling Powder may be related to the up-regulation of β-AR and the increase of cAMP level, and the combination therapy may improve the efficacy of glucocorticoids.