通过检测ＩＬ２及ｓＩＬ２Ｒ，了解肺外结核患者的免疫功能及与肺结核患者免疫功能的区别。采用双抗体夹心ＥＬＳＡＳ法分别测定了３０例肺结核和２８例肺外结核患者血清中的ＩＬ２及ｓＩＬ２Ｒ水平，并在抗结核化疗３个月后再次测定，结果显示肺外结核患者血清ＩＬ２明显低于肺结核患者（Ｐ＜０００１），而其ｓＩＬ２Ｒ却明显高于后者（Ｐ＜０００１）；经抗结核化疗３个月后肺外结核患者血清中的ＩＬ２明显升高而ｓＩＬ２Ｒ明显降低，与肺结核患者同期相比无显著差异（Ｐ＞００５）。由此可见Ｔ细胞活化后ｓＩｌ２Ｒ表达增强作为免疫封闭因子，是造成肺外结核免疫功能低下的主要原因 By detecting IL 2 and sIL 2R, to understand the immune function of patients with pulmonary tuberculosis and pulmonary tuberculosis patients with immune function difference. IL-2 and sIL-2R levels in 30 patients with tuberculosis and 28 patients with extrapulmonary tuberculosis were measured by ELSAS sandwich ELISA and determined again 3 months after anti-TB chemotherapy. The results showed that the serum levels of extra-pulmonary tuberculosis IL-2 was significantly lower than that of patients with pulmonary tuberculosis (P <0001), but the sIL2R was significantly higher than the latter (P <0001); 3 months after anti-TB chemotherapy in patients with extrapulmonary tuberculosis serum Significantly increased IL 2 and sIL 2R decreased significantly, compared with the same period in patients with tuberculosis no significant difference (P> 0  05). This shows that T cell activation sIl  2R enhanced expression as an immune block factor is caused by pulmonary tuberculosis immune dysfunction, the main reason