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1背景基于向成员国提供卫生政策指导的职责,世界卫生组织(World Health Organization,WHO)发布了一系列疫苗或疫苗制品定期更新的立场文件,这些疫苗或疫苗制品可预防具有国际公共卫生影响的疾病。最近的百日咳疫苗使用立场文件于2010年出版,包括以下内容和建议:(1)无细胞百日咳疫苗(Acellular Pertussis Vaccine,a P)和全细胞百日咳疫苗(Whole Cell Pertussis Vaccine,w P)的效力取决于百日咳的病例定义。然而,在预防百日咳的效力上,最好aP虽然高于低效力w P,但可能会低于最高效力w P。数据表明,在低发病率人群中使
1 Background Based on its responsibility to provide guidance to member countries on health policy, the World Health Organization (WHO) issued a series of position papers on a regular basis for the update of vaccines or vaccine products that could prevent the impact of international public health impacts disease. The recent publication of the position paper on pertussis vaccines was published in 2010 and includes the following and recommendations: (1) The efficacy of Acellular Pertussis Vaccine (aP) and Whole Cell Pertussis Vaccine (wP) depends on Case definition for pertussis. However, in the prophylaxis of pertussis, it is preferable that aP, although higher than the low potency WP, may be below the highest potency WP. The data show that it is made in low-prevalence populations