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目的探讨药物洗脱支架置入后支架内亚急性血栓形成的因素及治疗措施。方法回顾性分析15例置入药物洗脱支架后发生支架内亚急性血栓患者的临床资料。结果 15例患者中急性心肌梗死8例,支架内血栓形成发生于支架置入后36h~5d;血栓形成后12例行急诊冠状动脉内尿激酶溶栓,11例存活,1例死亡;3例未行冠状动脉尿激酶溶栓者中1例存活,2例死亡。结论急性心肌梗死为支架内亚急性血栓形成的高危因素,冠状动脉内尿激酶溶栓治疗,可改善患者预后。
Objective To investigate the factors and treatment of subacute thrombosis in stent after drug-eluting stent implantation. Methods The clinical data of 15 patients with sub-acute stent thrombosis after drug-eluting stents were retrospectively analyzed. Results Of the 15 patients, 8 had acute myocardial infarction and the stent thrombosis occurred 36 h to 5 d after stent implantation. In 12 patients undergoing thrombolysis, emergency coronary urokinase thrombolysis was performed, 11 survived and 1 died. Three patients One of the patients who did not undergo coronary urokinase thrombolysis survived and two died. Conclusion Acute myocardial infarction is a risk factor for sub-acute stent thrombosis. Urokinase thrombolytic therapy in coronary artery can improve the prognosis of patients.