本实验采用国产新型材料——卡波姆为基质,以甲硝唑为主药,研制了复方甲硝唑口腔溃疡凝胶剂,克服了膜剂、软膏剂及散剂的缺点,增加了药物的治疗效果,并初步考察了该制剂的稳定性。1 药品与仪器 甲硝唑标准品(威海新华制药厂);卡波姆(市售);地塞米松、盐酸达可罗宁(市售),其它试剂均为 In this study, a new type of domestic material - carbomer as the matrix to metronidazole as the main drug, developed a compound metronidazole oral ulcer gel, overcoming the shortcomings of the film, ointment and powder, increasing the drug Therapeutic effect, and preliminary study of the stability of the preparation. 1 drugs and equipment Metronidazole standard (Weihai Xinhua Pharmaceutical Factory); Carbopol (commercial); dexamethasone, dacronide hydrochloride (commercially available), other reagents are