1　临床资料患儿女,9岁,无诱因咽痛1个月,颜面浮肿、尿少15ｄ,未就医;因剧烈头痛伴喷射性呕吐、昏迷、抽搐数小时而入当地医院,拟诊“急性肾炎合并高血压脑病及急性肾功能衰竭”,予“硝普钠”、“甘露醇”等治疗10ｄ。尿量渐增至1000ｍｌ/ｄ,但仍昏迷,抽搐及呕吐未缓解,于1995- 1 clinical data Children, 9 years old, no incentive to sore throat for 1 month, facial edema, oliguria 15d, did not seek medical treatment; due to severe headache with jet vomiting, coma, convulsions and hours into the local hospital, to be diagnosed with “acute Nephritis with hypertensive encephalopathy and acute renal failure ”, to“ sodium nitroprusside ”,“ mannitol ”and other treatment 10d. Increasing urine output to 1000ml / d, but still coma, convulsions and vomiting did not ease, in 1995-