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用国产病毒唑治疗84例慢性丙肝患者,0.6~0.9克/天,分3次口服,用药6月。疗程结束时大部分患者临床症状减轻或消失,部分患者肝脏回缩,47.6%的患者血清ALT恢复正常。42.5%的患者HCV-RNA转阴。但停药后随访6~12月,血清ALT仅有5;95%患者持续正常,复发率为87.5%(35l40)。血清HCV~RNA仅有7.6%的患者持续阴转,复发率为81.8%(18/22)。
With domestic ribavirin treatment of 84 patients with chronic hepatitis C, 0.6 to 0.9 g / day, 3 times orally, medication in June. At the end of the course of treatment, the clinical symptoms of most patients were alleviated or disappeared. Some patients had liver contractures, and 47.6% of the patients returned to normal serum ALT. In 42.5% of patients, HCV-RNA turned negative. However, after stopping the treatment from 6 to 12 months, serum ALT was only 5; 95% of patients continued normal, the recurrence rate was 87.5% (35l40). Serum HCV ~ RNA only 7.6% of patients with persistent overcast, the recurrence rate was 81.8% (18/22).