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我院收治一例27天婴儿,发热、烦躁、抽风、肢端发绀,心率192次/分。腰穿脑脊液呈淡黄绿色,细胞数2480/mm~3,蛋白700mg/dl,氯化物622mg/dl,涂片镜检革兰氏阴性杆菌占多数。出血时间为零(挤不出血),凝血时间30秒。诊断为化脓性脑膜炎入院。脑脊液培养生长鼠伤寒杆菌,故诊断为鼠伤寒杆菌脑膜炎。因死后心血培养生长鼠伤寒杆菌,可考虑为鼠伤寒杆菌败血症,但临床表现以脑膜炎体征为突出。今后遇新生儿脑膜炎患者,亦应想到鼠伤寒杆菌脑膜炎之可能。
A 27-day-old infant was admitted to our hospital for fever, irritability, ventilation, acromegaly, and heart rate 192 beats / min. Lumbar cerebrospinal fluid was pale yellow green, the number of cells 2480 / mm ~ 3, protein 700mg / dl, chloride 622mg / dl, smear microscopy Gram-negative bacilli accounted for the majority. Bleeding time is zero (squeeze hemorrhage), clotting time 30 seconds. Diagnosis of purulent meningitis admitted. Cerebrospinal fluid growth in Salmonella typhimurium, it is diagnosed as Salmonella typhimurium meningitis. Growth of Salmonella typhimurium due to post-mortem blood culture, can be considered as Salmonella typhimurium sepsis, but the clinical manifestations of meningitis signs. In the future case of neonatal meningitis, should also think of Salmonella typhimurium meningitis possible.