大骨节病是一种地方性骨关节病;主要发生在儿童及少年,其早期病变的特征,是关节软骨及骺板软骨深层肥大细胞坏死,并发生修复性改变,引起骨骺早期化骨,致成侏儒及骨关节病。大骨节病原因不清,动物实验模型未能建立。79年有 VE 及硒治疗大骨节病有效的 Kaschin-Beck disease is a endemic osteoarthrosis; mainly occurs in children and adolescents, the characteristics of its early lesions, is the articular cartilage and epiphyseal cartilage deep mast cell necrosis, and the occurrence of repair changes, causing epiphyseal early bone, resulting in Into dwarf and bone and joint disease. Kashin-Beck disease causes unclear, animal experimental model failed to establish. 79 years of VE and selenium treatment of Kashin-Beck disease effective