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目的:探讨头痛宁胶囊联合黛力新、乙哌立松治疗紧张性头痛的临床疗效。方法:筛选2014年1月至2015年1月本院收治的紧张性头痛患者96例作为研究对象。采用随机数表法将所有患者分为观察组与对照组,每组48例,其中对照组患者采用黛力新、乙哌立松治疗,观察组在对照组基础上给予头痛宁胶囊治疗,两组患者共治疗4周,统计两组患者治疗前后症状改善及治疗总有效率,并比较两组患者不良反应发生情况。结果:两组患者治疗前发作次数、持续时间、疼痛强度评分比较,差异无统计学意义(P>0.05),治疗后均显著改善,但观察组治疗后发作次数、持续时间、疼痛强度改善效果更为明显,与对照组比较,差异具有统计学意义(P<0.05);观察组治疗后总有效率95.83%明显高于对照组的77.08%,差异具有统计学意义(P<0.05);观察组治疗后不良反应发生率与对照组比较,差异无统计学意义(P>0.05)。结论:头痛宁胶囊联合黛力新、乙哌立松治疗紧张性头痛疗效确切,可有效降低头痛发作次数、持续时间及疼痛强度,并且并发症发生率较低,安全性高。
Objective: To investigate the curative effect of Toutongning capsule combined with Deanxit and Eperisone in the treatment of tension headache. Methods: A total of 96 patients with tension headache admitted from January 2014 to January 2015 in our hospital were screened out. All patients were divided into observation group and control group using random number table method, 48 cases in each group. The patients in the control group were treated with dextromethorphan and eperisone. The observation group was treated with Toutanting capsule on the basis of the control group. Two groups The patients were treated for 4 weeks. The improvement of symptoms and the total effective rate of the two groups before and after treatment were statistically analyzed. The incidence of adverse reactions was compared between the two groups. Results: There was no significant difference in the number of seizures, duration and intensity of pain between the two groups before treatment (P> 0.05), but after treatment, the number of seizures, duration and intensity of pain were significantly improved (P <0.05). The total effective rate in observation group was 95.83%, which was significantly higher than that in control group (77.08%), the difference was statistically significant (P <0.05). The difference was statistically significant (P <0.05) There was no significant difference in the incidence of adverse reactions between the two groups after treatment (P> 0.05). Conclusion: Touttongning capsule combined with Deanin, Eperisone treatment of tension headache curative effect is exact, can effectively reduce the number of headache attacks, duration and pain intensity, and the incidence of complications is low, high safety.