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目的:分析心脏彩超检查联合N末端B型脑钠肽前体(NT-proBNP)水平监测对老年危重症机械通气患者撤机结果的预测价值。方法:抽取2019年1月至2020年12月于太原钢铁总医院行机械通气的老年危重症患者89例，根据自主呼吸试验标准进行撤机，统计48 h内撤机成功和撤机失败情况。比较撤机成功与失败者撤机前达到自主呼吸试验标准时心脏彩超参数及血清NT-proBNP水平，绘制受试者工作曲线并计算曲线下面积(AUC)，分析相关指标对老年危重症患者撤机结果的预测价值。结果:89例中撤机成功68例，撤机失败21例。撤机失败者舒张早期左房室瓣血流速度(E)/舒张早期左房室瓣环运动速度(E\')、收缩期左心房面积(LAA)、血清NT-proBNP水平分别为10.22±2.15、(24.08±3.36)cmn 2、(338.74±69.75)pg/ml，高于撤机成功者的相应值(n t＝4.424、5.176、3.686，n P0.05。E/E\'、LAA、血清NT-proBNP水平单项及联合预测老年危重症患者撤机失败风险的AUC均>0.80，预测价值均理想，且以联合预测价值较佳。n 结论:心脏彩超参数E/E\'、LAA及血清NT-proBNP水平对老年危重症机械通气患者撤机结果有一定预测价值，三者高表达提示老年危重症机械通气患者撤机失败的风险较高。“,”Objective:To analyze the value of color Doppler echocardiography combined with N-terminal pro brain natriuretic peptide (NT-proBNP) level monitoring in predicting weaning outcome in elderly patients with critically ill undergoing mechanical ventilation.Methods:A total of 89 critically ill elderly patients who underwent mechanical ventilation in Taiyuan Iron and Steel General Hospital from January 2019 to December 2020 were selected. They were weaned by the standard of spontaneous breathing test, and the success and failure of weaning within 48 hours were counted. The cardiac color Doppler ultrasound parameters and serum NT-proBNP level when the successful and unsuccessful weaning meet the standard of the spontaneous breathing test before weaning were compared, draw the receiver operating curve and calculate the area under the curve (AUC), and the predictive value of relevant indicators for the weaning of elderly critically ill patients were analyzed.Results:Among the 89 cases, 68 cases were successfully weaned and 21 cases failed. The early diastolic velocity of left atrioventricular valve (E)/ early diastolic velocity of left atrioventricular annulus (E’), systolic left atrial area (LAA), and serum NT-proBNP level were 10.22±2.15, (24.08±3.36) cmn 2, (338.74±69.75) pg/ml, which were higher than the response values of successful weaning (n t=4.424, 5.176, 3.686, n P0.05. The AUC of E/E\', LAA, and serum NT-proBNP level single item and combined predicting the risk of weaning failure in elderly critically ill patients were all more than 0.80, and the predictive value was ideal, and the combined predictive value was better.n Conclusions:The levels of E/E\', LAA and serum NT proBNP in color Doppler ultrasound parameters have certain predictive value for weaning outcome of elderly critically ill patients. The high expression of these three parameters indicates that the risk of weaning failure is higher in elderly critically ill patients.