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血、尿β_2微球蛋白(β_2M)测定是判断肾功能变化的一项灵敏而可靠的指标。在小儿原发性肾小球疾病中部分病例的血和/或尿β_2M显示不同程度的升高,提示了肾小球和/或肾小管功能的受损情况。为了探讨其不同病理类型与血、尿β_2M变化的关系,我院于1986年1月～1991年8月对住院的122例原发性肾小球疾病患儿作了肾穿刺活检,并同时检测血、尿β_2M作对照分析,现将结果报告如下。
Determination of blood and urine β_2 microglobulin (β_2M) is a sensitive and reliable indicator of changes in renal function. In some cases of pediatric primary glomerular disease blood and / or urinary β_2M showed varying degrees of elevation, suggesting a compromised glomerular and / or tubular function. In order to explore the relationship between the different pathological types and blood and urine β_2M changes, our hospital from January 1986 to August 1991 hospitalized 122 cases of primary glomerular disease in children with renal biopsy and simultaneous detection Blood, urine β_2M for control analysis, the results are reported as follows.