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目的讨论不同治疗方法在剖宫产后子宫切口妊娠的临床治疗效果。方法分别选择19例患者作为观察组和对照组。其中对照组使用肌肉注射甲氨蝶呤并口服米非司酮的治疗方法,观察组用氯化钠稀释甲氨蝶呤后,在阴式超声下对孕囊直接注稀释液,并同时口服米非司酮。统计两组治疗效果和血β-HCG转阴时间,以评价两种治疗方法在剖宫产后子宫切口妊娠的临床治疗效果。结果观察组治愈34例,无效4例,成功率为89.5%;对照组治愈27例,无效11例,成功率为71.5%。两组治疗成功率比较差异有统计学意义(P<0.05)。就血β-HCG转阴时间来看,观察组转阴时间为(9.2±2.9)d,与对照组的(15.3±3.6)d相比,差异有统计学意义(P<0.05)。结论使用氯化钠稀释甲氨蝶呤治疗剖宫产后子宫切口妊娠可以有效提高治疗成功率,并缩短患者血β-HCG转阴时间,值得在临床中推广使用。
Objective To discuss the clinical effect of different treatment methods in uterine incision pregnancy after cesarean section. Methods Nineteen patients were selected as observation group and control group respectively. The control group was treated with intramuscular injection of methotrexate and oral mifepristone. The observation group was diluted with sodium chloride methotrexate, and the gestational sac was directly injected with diluent under vaginal ultrasound with simultaneous oral administration of rice Nesslerone. The treatment effect and blood β-HCG negative time of the two groups were statistically evaluated in order to evaluate the clinical effect of the two treatment methods in cesarean section pregnancy after cesarean section. Results The observation group cured 34 cases, 4 cases were ineffective, the success rate was 89.5%; control group, 27 cases were cured, 11 cases were ineffective, the success rate was 71.5%. The difference between the two groups was statistically significant (P <0.05). In terms of blood β-HCG negative conversion time, the observation group was (9.2 ± 2.9) days, which was significantly lower than that in the control group (15.3 ± 3.6) days (P <0.05). Conclusion The use of sodium chloride diluted methotrexate in the treatment of uterine incision pregnancy after cesarean section can effectively improve the success rate of treatment, and shorten the blood β-HCG in patients with negative conversion time, it is worth to promote the use of the clinic.